Article
Multiple sclerosis in the tropics: genetic association to STR's loci spanning the HLA and TNF.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2002
Palacio L G, Rivera D, Builes J J, Jiménez M E, Salgar M, Anaya J M, Jiménez I, Camargo M, Arcos-Burgos M, Sánchez J L
Abstract excerpt
Clear evidence has been presented correlating gene polymorphisms at 6p21.3-21.4 (containing HLA and TNF) and the predisposition to acquire multiple sclerosis (MS). In a previous study, we found that polymorphisms at HLA DQAI were associated with being or not being predisposed to MS in individuals inhabiting the tropics, where the prevalence of MS is significantly lower than in subtropical areas. Here, we tested...
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