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Article

SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Jan 2001

Rossi L, Pfützer R H, Parvin S, Ali L, Sattar S, Kahn A K, Gyr N, Whitcomb D C

Abstract excerpt

BACKGROUND/AIMS: Tropical pancreatitis (TP) refers to a severe type of idiopathic chronic pancreatitis that develops in children in tropical regions of Africa and southern Asia. Phenotypically TP is subdivided into fibrocalculous pancreatic diabetes (FCPD) and tropical calcific pancreatitis without diabetes mellitus (TCP). Recently an association was identified between idiopathic pancreatitis in the USA and...

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Source

Identifiers

PMID: 12120202
DOI: 10.1159/000055818

Genes

SPINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.PMID 12120202Read ↗

SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh.Semantic proximity Read ↗

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A SPINK1 gene mutation in a Thai patient with fibrocalculous pancreatic diabetes.Semantic proximity Read ↗

Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.Semantic proximity Read ↗

SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent.Semantic proximity Read ↗

Idiopathic chronic pancreatitis in India: phenotypic characterisation and strong genetic susceptibility due to SPINK1 and CFTR gene mutations.Semantic proximity Read ↗

SPINK1 mutations are associated with multiple phenotypes.Semantic proximity Read ↗

Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis.Semantic proximity Read ↗

Pancreatitis in fibrocalculous pancreatic diabetes mellitus is not associated with common mutations in the trypsinogen gene.Semantic proximity Read ↗

Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants.Semantic proximity Read ↗

Mutations in the pancreatic secretory trypsin inhibitor gene (<i>PSTI</i>/<i>SPINK1</i>) rather than the cationic trypsinogen gene (<i>PRSS1</i>) are significantly associated with tropical calcific pancreatitisSemantic proximity Read ↗

SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.Semantic proximity Read ↗

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