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Article

Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants.

European journal of gastroenterology & hepatology - 1 Aug 2009

Derikx Monique H M, Szmola Richard, te Morsche Rene H M, Sunderasan Santhosh, Chacko Ashok, Drenth Joost P H

Abstract excerpt

BACKGROUND: Tropical calcific pancreatitis (TCP) is a relatively common form of chronic pancreatitis in parts of Asia and Africa. The SPINK1 variant p.N34S is strongly associated with TCP, but other genetic factors remain to be defined. Chymotrypsinogen C (CTRC) degrades trypsinogen and loss-of-f...

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Source

Identifiers

PMID: 19404200
DOI: 10.1097/MEG.0b013e32832183cf

Genes

CTRC
SPINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19404200-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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