Article
SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent.
American journal of human genetics - 1 Oct 2002
Hassan Zahid, Mohan Viswananthan, Ali Liaquat, Allotey Rebecca, Barakat Khalid, Faruque M Omar, Deepa Raj, McDermott Michael F, Jackson Alan E, Cassell Paul, Curtis David, Gelding Susan V, Vijayaravaghan Shanti, Gyr Niklaus, Whitcomb David C, Khan A K Azad, Hitman Graham A
Abstract excerpt
Fibrocalculous pancreatic diabetes (FCPD) is a secondary cause of diabetes due to chronic pancreatitis. Since the N34S variant of the SPINK1 trypsin inhibitor gene has been found to partially account for genetic susceptibility to chronic pancreatitis, we used a family-based and case-control approach in two separate ethnic groups from the Indian subcontinent, to determine whether N34S was associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.