Article
The frequency of pre-core gene mutations in chronic hepatitis B infection: a study of Malaysian subjects.
The Southeast Asian journal of tropical medicine and public health - 1 Mar 2002
Yap S F, Wong P W, Chen Y C, Rosmawati M
Abstract excerpt
A retrospective study was carried out to determine the frequency of the pre-core stop codon mutant virus in a group of chronic hepatitis B carriers: 81 cases were considered [33 hepatits B e antigen (HBe) positive and 48 HBe negative]. All of the HBe positive cases had detectable viral DNA by hybridization analysis; in the case of the HBe negative cases, one third had detectable viral DNA by hybridization...
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