Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4.

doi:10.1038/ng932

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Article

Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4.

Nature genetics - 1 Aug 2002

Feng Bing-Jian, Huang Wei, Shugart Yin Yao, Lee Ming K, Zhang Feng, Xia Jian-Chuan, Wang Hui-Yun, Huang Teng-Bo, Jian Shao-Wen, Huang Ping, Feng Qi-Sheng, Huang Li-Xi, Yu Xing-Juan, Li Duang, Chen Li-Zheng, Jia Wei-Hua, Fang Yan, Huang Hui-Ming, Zhu Jing-Liu, Liu Xiao-Ming, Zhao Yan, Liu Wang-Qing, Deng Mang-Quan, Hu Wei-Han, Wu Shao-Xiong, Mo Hao-Yuan, Hong Ming-Fang, King Mary Claire, Chen Zhu, Zeng Yi-Xin

Abstract excerpt

Nasopharyngeal carcinoma (NPC) occurs with high frequency in Asian populations, especially among people of Cantonese ancestry. In areas with high incidence, NPC clusters in families, which suggests that both geography and genetics may influence disease risk. Although the HLA-Bw46 locus is associated with increased risk of NPC, no predisposing genes have been identified so far. Here we report the results of a...

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PMID: 12118254
DOI: 10.1038/ng932

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