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Meta-analysis of Epstein-Barr virus genomes in Southern Chinese identifies genetic variants and high risk viral lineage associated with nasopharyngeal carcinoma.

PLoS pathogens - 1 May 2024

Wong Ka Wo, Hui Kwai Fung, Lam Ki Pui, Kwong Dora Lai-Wan, Lung Maria Li, Yang Wanling, Chiang Alan K S

Abstract excerpt

Genetic variants in Epstein-Barr virus (EBV) have been strongly associated with nasopharyngeal carcinoma (NPC) in South China. However, different results regarding the most significant viral variants, with polymorphisms in EBER2 and BALF2 loci, have been reported in separate studies. In this study, we newly sequenced 100 EBV genomes derived from 61 NPC cases and 39 population controls. Comprehensive genomic...

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Identifiers

PMID: 38805547
DOI: 10.1371/journal.ppat.1012263
PMCID: PMC11161099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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