Article
Diverse dependencies of developing Merkel innervation on the trkA and both full-length and truncated isoforms of trkC
1 Aug 2002
Abstract excerpt
This study demonstrates that innervation dependent on two different neurotrophin tyrosine kinase (trk) receptors can form the same types of sensory endings (Merkel endings) in the same target (Merkel cells of vibrissa follicles). Some endings transiently express trkA during their initial development, whereas others express trkC throughout their development. Consequently, elimination of kinase domains of either...
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