Article
Dual innervation of neonatal Merkel cells in mouse touch domes.
PloS one - 1 Jan 2014
Niu Jingwen, Vysochan Anna, Luo Wenqin
Abstract excerpt
Merkel cell-neurite complexes are specialized mechanosensory end organs that mediate discriminative touch sensation. It is well established that type I slowly adapting (SAI) mechanoreceptors, which express neural filament heavy chain (NFH), innervate Merkel cells. It was previously shown that neurotrophic factor NT3 and its receptor TrkC play crucial roles in controlling touch dome Merkel cell innervation of NFH+...
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