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Neurotrophins Act as Neuroendocrine Regulators of Skin Homeostasis in Health and Disease

1 Feb 2007

Abstract excerpt

Neurotrophins regulate cutaneous innervation, act as growth and motility factors on structural skin cells such as keratinocytes and fibroblasts, modulate cutaneous immune function and even serve as stress mediators in skin biology. The multilayered neurotrophin interaction with skin biology through high affinity specific tyrosinekinase receptors and the Janus-faced p75 receptor, which depending on ligand and...

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Identifiers

PMID: 17326007
DOI: 10.1055/s-2007-961812

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