Article
Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study.
Archives of neurology - 1 Jul 2002
Leverenz James B, Agustin Christina M, Tsuang Debby, Peskind Elaine R, Edland Steven D, Nochlin David, DiGiacomo Lillian, Bowen James D, McCormick Wayne C, Teri Linda, Raskind Murray A, Kukull Walter A, Larson Eric B
Abstract excerpt
BACKGROUND: Hippocampal sclerosis (HS) is a neuropathologic finding characterized by neuronal loss and gliosis in the CA-1 and subiculum of the hippocampus. Previous studies of HS have shown that this is a common postmortem finding in elderly subjects with dementia. However, these studies were from selected samples and therefore are not necessarily representative of patients seen in the general medical community....
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