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Article

Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project.

The lancet. Healthy longevity - 1 Aug 2023

Garo-Pascual Marta, Gaser Christian, Zhang Linda, Tohka Jussi, Medina Miguel, Strange Bryan A

Abstract excerpt

BACKGROUND: Cognitive abilities, particularly memory, normally decline with age. However, some individuals, often designated as superagers, can reach late life with the memory function of individuals 30 years younger. We aimed to characterise the brain structure of superagers and identify demographic, lifestyle, and clinical factors associated with this phenotype. METHODS: We selected cognitively healthy...

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PMID: 37454673
DOI: 10.1016/S2666-7568(23)00079-X
PMCID: PMC10397152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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