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Article

Alzheimer neuropathologic alterations in aged cognitively normal subjects.

Journal of neuropathology and experimental neurology - 1 Apr 1999

Davis D G, Schmitt F A, Wekstein D R, Markesbery W R

Abstract excerpt

The histopathologic changes distinguishing early Alzheimer disease (AD) from normal or pathologic aging are not clearly defined. This report describes the autopsy findings of 59 elderly, well-educated, volunteers. They were examined longitudinally with mental status testing, some for up to 8 years, as part of our normal aging study. This study reveals that (1) the brains of many subjects who did not show...

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PMID: 10218633
DOI: 10.1097/00005072-199904000-00008

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