Sensitivity and resistance of pathogenic yeasts to 5-fluoropyrimidines. II.--Mechanisms of resistance to 5-fluorocytosine (5-FC) and 5-fluorouracil (5-FU) (author's transl).

Article

Sensitivity and resistance of pathogenic yeasts to 5-fluoropyrimidines. II.--Mechanisms of resistance to 5-fluorocytosine (5-FC) and 5-fluorouracil (5-FU) (author's transl).

Annales de microbiologie - 1 Jan 2000

Montplaisir S, Drouhet E, Mercier-Soucy L

Abstract excerpt

Incorporation of labelled 14C-pyrimidines and 5-fluoropyrimidines (5-FC and 5-FU) in four different phenotypes of wild strains of Candida isolated from man showed comparable results to those obtained by the minimal inhibition concentration (MIC) test. Kinetics studies demonstrated significant rat...

Topics

Candida
Cytosine
Drug Resistance, Microbial
Flucytosine
Fluorouracil
Kinetics
Phenotype
Species Specificity

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