Article
Genetic resistance to malaria in mouse models.
Trends in parasitology - 1 Aug 2005
Hernandez-Valladares Maria, Naessens Jan, Iraqi Fuad A
Abstract excerpt
Murine models have proved to be excellent tools in the support of studies of the human genetic bases of malaria resistance and have enabled the mapping of 12 resistance loci, eight of them controlling parasitic levels and four controlling cerebral malaria. Further studies using this method have identified a Pklr variant that confers resistance to murine malaria, a result that shows the potential of this approach...
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