Article
Expression of ErbB3, ErbB4, and neuregulin-1 mRNA during tooth development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2002
Fried K, Risling M, Tidcombe H, Gassmann M, Lillesaar C
Abstract excerpt
The receptor tyrosine kinases ErbB3 and ErbB4, which bind to various variants of neuregulin (NRG), play fundamental roles in neural development and in organs, which form through epithelial-mesenchymal interactions. Here, we demonstrate that NRG-1 and the receptors ErbB3 and ErbB4 are expressed locally during rodent tooth development. However, the mRNA expression patterns of ErbB3 and ErbB4 were distinctly...
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