Article
The impact of genotype on outcome in oligodendroglioma: validation of the loss of chromosome arm 1p as an important factor in clinical decision making.
Journal of neurosurgery - 1 Apr 2006
Kanner Andrew A, Staugaitis Susan M, Castilla Elias A, Chernova Olga, Prayson Richard A, Vogelbaum Michael A, Stevens Glen, Peereboom David, Suh John, Lee Shih-Yuan, Tubbs Raymond R, Barnett Gene H
Abstract excerpt
OBJECT: Oligodendrogliomas are rare primary brain tumors. They comprise approximately 5 to 33% of all glial tumors but differ from astrocytomas by being associated with a more favorable prognosis, making their correct identification important. Allelic loss of chromosome arms 1p and 19q is found in a substantial subpopulation of tumors with an oligodendroglioma phenotype. Anaplastic oligodendrogliomas with allelic...
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