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Oligodendroglioma cell lines containing t(1;19)(q10;p10)

13 Apr 2010

Abstract excerpt

Investigating the biology of oligodendroglioma and its characteristic combined deletion of chromosomal arms 1p and 19q, mediated by an unbalanced translocation, t(1;19)(q10;p10), has been hampered by the lack of cell lines that harbor these traits. We grew cells from 2 anaplastic oligodendrogliomas in serum-free conditions. Serial propagation and expansion led to the establishment of permanent cell lines that...

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PMID: 20388696
DOI: 10.1093/neuonc/noq031

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