Article
Equivalent parental distribution of frequently lost alleles and biallelic expression of the H19 gene in human testicular germ cell tumors.
Japanese journal of cancer research : Gann - 1 Aug 1996
Mishina M, Ogawa O, Kinoshita H, Oka H, Okumura K, Mitsumori K, Kakehi Y, Reeve A E, Yoshida O
Abstract excerpt
Epigenetic alterations such as genomic imprinting might play an important role in human tumorigenesis, in addition to specific genetic alterations. To clarify the role of genetic and/or epigenetic alterations in the tumorigenesis of testicular germ cell tumors (GCTs), we analyzed 40 primary and 3...
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 11
- Gene Expression
- Genes, Tumor Suppressor
- Genomic Imprinting
- Germinoma
- Heterozygote
- Humans
- Lymphatic Metastasis
- Male
- Molecular Sequence Data
- Muscle Proteins
- Polymerase Chain Reaction
