Article
Evolutionary conserved microsatellites in the promoter region of the 5-hydroxytryptamine receptor 2C gene (HTR2C) are not associated with bipolar disorder in females.
Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2002
Meyer J, Saam W, Mössner R, Cangir O, Ortega G R, Tatschner T, Riederer P, Wienker T F, Lesch K P
Abstract excerpt
Two polymorphic dinucleotide repeats separated by a short spacer are localized in the promoter region of the serotonin receptor 2C gene ( HTR2C). One of the repeats was found to be evolutionary conserved between humans and rhesus monkeys. Although promoter-associated microsatellites have previously been shown to regulate expression of different genes, we did not find any significant influence of distinct HTR2C...
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