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Article

Strategies for genome-wide association studies: optimization of study designs by the stepwise focusing method.

Journal of human genetics - 1 Jan 2002

Saito Akira, Kamatani Naoyuki

Abstract excerpt

Recently, the use of genome-wide linkage disequilibrium (LD) analysis to localize traits has attracted much attention because of the introduction of high-throughput genotyping systems. However, a limitation of such studies is often the total cost of genotyping in addition to sample size. Therefore, it is important to estimate optimal conditions for such a study given the total cost of genotyping. In the present...

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PMID: 12111370
DOI: 10.1007/s100380200050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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