Article
C825T polymorphism of the G protein beta3 subunit is associated with obesity but not with insulin sensitivity.
Obesity research - 1 Apr 2004
Stefan Norbert, Stumvoll Michael, Machicao Fausto, Koch Matthias, Häring Hans U, Fritsche Andreas
Abstract excerpt
OBJECTIVE: The common C825T polymorphism of the gene that encodes the G protein beta3 subunit has been shown to influence lipolysis in human adipocytes and to be associated with hypertension, body fat distribution, and obesity. In addition, it has been shown to be associated with insulin resistance in a small group of hypertensive subjects. We investigated whether this polymorphism contributed to the variability...
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