Article
Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins.
Pharmacogenetics - 1 Jul 2004
Dong Yanbin, Zhu Haidong, Wang Xiaoling, Dalageorgou Chrysoula, Carter Nick, Spector Tim D, Snieder Harold
Abstract excerpt
The 825C>T polymorphism of the G-protein beta3-subunit gene (GNB3) has been associated with hypertension, although results are not entirely consistent. In a sample of 282 female Caucasian dizygotic twins aged 21-80 years, we aimed to investigate the associations between blood pressure and five single nucleotide polymorphisms (SNPs) including the 825C>T and haplotypes of the GNB3 gene. The polymorphisms (-350A>G,...
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