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Article

Peroxisome proliferators: potential role of altered hepatocyte growth and differentiation in tumor development.

Progress in clinical and biological research - 1 Jan 1995

Cattley R C, Miller R T, Corton J C

Abstract excerpt

Continued, exposure-dependent proliferation of hepatocytes in basophilic proliferative lesions appears to be critical to the mechanism of peroxisome proliferator carcinogenesis in rodents. Identification of the growth regulatory pathway(s) involved in the exaggerated hepatocellular proliferation observed in these lesions is proceeding. So far, regulatory pathways involving cyclophilin and IGFII/M6P receptor have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 8532723

Genes

HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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