Article
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation.
The Journal of cell biology - 8 Jul 2002
Weston Andrea D, Chandraratna Roshantha A S, Torchia Joseph, Underhill T Michael
Abstract excerpt
Chondrogenesis is a multistep process culminating in the establishment of a precisely patterned template for bone formation. Previously, we identified a loss in retinoid receptor-mediated signaling as being necessary and sufficient for expression of the chondroblast phenotype (Weston et al., 2000. J. Cell Biol. 148:679-690). Here we demonstrate a close association between retinoic acid receptor (RAR) activity and...
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