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Article

The transcriptional activity of Sox9 in chondrocytes is regulated by RhoA signaling and actin polymerization.

Molecular and cellular biology - 1 Aug 2009

Kumar Deepak, Lassar Andrew B

Abstract excerpt

In this study, we demonstrate that dedifferentiation of round primary chondrocytes into a fibroblast morphology correlates with a profound induction of RhoA protein and stress fibers. Culture of dedifferentiated chondrocytes in alginate gel induces a precipitous loss of RhoA protein and a loss of stress fibers concomitant with the reexpression of the chondrocyte differentiation program. We have found that...

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Identifiers

PMID: 19470758
DOI: 10.1128/MCB.01779-08
PMCID: PMC2715793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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