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Article

Deciphering AP-1 Function in Tumorigenesis: Fra-ternizing on Target Promoters

1 Nov 2007

Abstract excerpt

Multi-gene families of transcription factors pose a formidable challenge to molecular and functional analysis. Dissecting distinct functions for individual family members requires a combination of approaches in different cellular and animal models. The AP-1 transcription factor complex serves as a paradigm for understanding the dynamics of transcriptional regulation. Knockout, knockdown and transgenic strategies,...

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Identifiers

PMID: 17957143
DOI: 10.4161/cc.6.21.4850

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