Article
Progressive appearance of pigmentation in amelanotic melanoma lesions.
Pigment cell research - 1 Aug 2002
Cohen-Solal Karine A, Crespo-Carbone Steven M, Namkoong Jin, Mackason Kerine R, Roberts Kathleen G, Reuhl Kenneth R, Chen Suzie
Abstract excerpt
We previously described a transgenic mouse line (TG-3) that spontaneously develops pigmented cutaneous melanoma. The generation of several albino mice that developed amelanotic melanoma has also been reported. In this report, we describe an unanticipated result with crosses between C57BL/6-c2j and TG-3 mice. C57BL/6-c2j has the same genetic background as TG-3 (C57BL/6), except for a single base mutation...
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