Article
Radiation-induced lung response of AcB/BcA recombinant congenic mice.
Radiation research - 1 Sept 2008
Lemay Anne-Marie, Haston Christina K
Abstract excerpt
The genetic factors that influence the development of radiotherapy-induced lung disease are largely unknown. Herein we identified a strain difference in lung response to radiation wherein A/J mice developed alveolitis with increased levels of pulmonary mast cells and cells in bronchoalveolar lavage while the phenotype in C57BL/6J mice was fibrosis with fewer inflammatory cells. To identify genomic loci that may...
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