Article
Normal thyroid thermogenesis but reduced viability and adiposity in mice lacking the mitochondrial glycerol phosphate dehydrogenase.
The Journal of biological chemistry - 6 Sept 2002
Brown Laura J, Koza Robert A, Everett Carrie, Reitman Marc L, Marshall Linda, Fahien Leonard A, Kozak Leslie P, MacDonald Michael J
Abstract excerpt
The mitochondrial glycerol phosphate dehydrogenase (mGPD) is important for metabolism of glycerol phosphate for gluconeogenesis or energy production and has been implicated in thermogenesis induced by cold and thyroid hormone treatment. mGPD in combination with the cytosolic glycerol phosphate dehydrogenase (cGPD) is proposed to form the glycerol phosphate shuttle, catalyzing the interconversion of...
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