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Article

Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice.

Redox biology - 1 Jan 2014

Bharadwaj Manish S, Zhou Yu, Molina Anthony J, Criswell Tracy, Lu Baisong

Abstract excerpt

Inner mitochondrial membrane peptidase 2-like (IMMP2L) protein is a mitochondrial inner membrane peptidase that cleaves the signal peptide sequences of cytochrome c1 (CYC1) and mitochondrial glycerol phosphate dehydrogenase (GPD2). Immp2l mutant mice show infertility and early signs of aging. It is unclear whether mitochondrial respiratory deficiency underlies this phenotype. Here we show that the intermediate...

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Source

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Identifiers

PMID: 25460737
DOI: 10.1016/j.redox.2014.08.006
PMCID: PMC4215389

Genes

CYC1
GPD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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