Article
Mobilization of dendritic cells from patients with breast cancer into peripheral blood stem cell leukapheresis samples using Flt-3-Ligand and G-CSF or GM-CSF.
Cytokine - 7 Apr 2002
Gasparetto Cristina, Gasparetto Maura, Morse Michael, Rooney Barbara, Vredenburgh James J, Long Gwynn D, Rizzieri David A, Loftis Jennifer, Chao Nelson J, Smith Clay
Abstract excerpt
Treatment with myeloablative chemotherapy and autologous peripheral blood stem cell (PBSC) transplantation followed by vaccination with autologous dendritic cells (DCs) treated with tumor antigens is a promising therapeutic strategy for several types of cancer. Obtaining sufficient numbers of both PBSCs and DCs is central to this approach. Previously, it has been shown that administration of Flt-3-Ligand (FL)...
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