Article
Comparison of CD34 and monocyte-derived dendritic cells from mobilized peripheral blood from cancer patients.
Stem cells (Dayton, Ohio) - 1 Jan 2005
Syme Rachel, Bajwa Rubinder, Robertson Laurie, Stewart Doug, Glück Stefan
Abstract excerpt
Dendritic cells (DCs) are potent antigen-presenting cells that are integral to the initiation of T-cell immunity. Two cell types can be used as a source for generating DCs: monocytes and CD34(+) stem cells. Despite many investigations characterizing DCs, none have performed a direct paired comparison of monocyte and stem cell-derived DCs. Therefore, it is unclear whether one cell source has particular advantages...
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