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Article

Regions of bacteriophage T4 and RB69 RegA translational repressor proteins that determine RNA-binding specificity.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1992

Jozwik C E, Miller E S

Abstract excerpt

RegA protein of T4 and related bacteriophages is a highly conserved RNA-binding protein that represses the translation of many phage mRNAs that encode enzymes involved in DNA metabolism. RB69, a T4-related bacteriophage, has a unique regA gene, which we have cloned, sequenced, and expressed. The predicted amino acid sequence of RB69 RegA is 78% identical to that of T4 RegA. Plasmid-encoded RB69 RegA expressed in...

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Topics

Amino Acid Sequence
Base Sequence
Cloning, Molecular
Gene Expression Regulation, Viral
Genes, Viral
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mutation

Protein Biosynthesis

RNA, Messenger

RNA-Binding Proteins

Repressor Proteins

Sequence Alignment

Structure-Activity Relationship

T-Phages

Viral Proteins

Viral Structural Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1594613
DOI: 10.1073/pnas.89.11.5053
PMCID: PMC49227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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