Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Widely Used Mutants of eiger, Encoding the Drosophila Tumor Necrosis Factor, Carry Additional Mutations in the NimrodC1 Phagocytosis Receptor.

G3 (Bethesda, Md.) - 3 Dec 2020

Kodra Albana, de la Cova Claire, Gerhold Abigail R, Johnston Laura A

Abstract excerpt

The process of apoptosis in epithelia involves activation of caspases, delamination of cells, and degradation of cellular components. Corpses and cellular debris are then rapidly cleared from the tissue by phagocytic blood cells. In studies of the Drosophila TNF, Eiger (Egr) and cell death in wing imaginal discs, the epithelial primordia of fly wings, we noticed that dying cells appeared to transiently accumulate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Mutation

Share to Receptors, Immunologic

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 33127847
DOI: 10.1534/g3.120.401800
PMCID: PMC7718733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Widely Used Mutants of eiger, Encoding the Drosophila Tumor Necrosis Factor, Carry Additional Mutations in the NimrodC1 Phagocytosis Receptor.PMID 33127847Read ↗

Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway.Semantic proximity Read ↗

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogasterSemantic proximity Read ↗

Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila.Semantic proximity Read ↗

EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removalSemantic proximity Read ↗

Drosophila eiger mutants are sensitive to extracellular pathogens.Semantic proximity Read ↗

Conserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell death.Semantic proximity Read ↗

Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling.Semantic proximity Read ↗

Phagocytosis promotes programmed cell death in C. elegans.Semantic proximity Read ↗

Somatic gonad sheath cells and Eph receptor signaling promote germ-cell death in C. elegans.Semantic proximity Read ↗

The Drosophila TNF ortholog eiger is required in the fat body for a robust immune response.Semantic proximity Read ↗

Dangerous liaisons: the apoptotic engulfment receptor CED-1 links innate immunity to the unfolded protein response.Semantic proximity Read ↗

Alternative Germ Cell Death Pathway in Drosophila Involves HtrA2/Omi, Lysosomes, and a Caspase-9 CounterpartSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.