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Article

Glial-derived prodegenerative signaling in the Drosophila neuromuscular system.

Neuron - 8 Dec 2011

Keller Lani C, Cheng Ling, Locke Cody J, Müller Martin, Fetter Richard D, Davis Graeme W

Abstract excerpt

We provide evidence for a prodegenerative, glial-derived signaling framework in the Drosophila neuromuscular system that includes caspase and mitochondria-dependent signaling. We demonstrate that Drosophila TNF-α (eiger) is expressed in a subset of peripheral glia, and the TNF-α receptor (TNFR),...

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Identifiers

PMID: 22153373
DOI: 10.1016/j.neuron.2011.09.031
PMCID: PMC3313621

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22153373-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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