Article
Role of paired basic residues of protein C-termini in phospholipid binding.
Protein engineering - 1 Jun 2002
Scheglmann Dietrich, Werner Knut, Eiselt Gabriele, Klinger Reinhard
Abstract excerpt
It is a well known phenomenon that the occurrence of several distinct amino acids at the C-terminus of proteins is non-random. We have analysed all Saccharomyces cerevisiae proteins predicted by computer databases and found lysine to be the most frequent residue both at the last (-1) and at the penultimate amino acid (-2) positions. To test the hypothesis that C-terminal basic residues efficiently bind to...
Topics
- Amino Acid Sequence
- Amino Acids, Basic
- Base Sequence
- Cell Membrane
- DNA, Fungal
- Molecular Sequence Data
- Mutation
- Phospholipids
- Protein Binding
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins