Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative lipid remodelling pathways for glycosylphosphatidylinositol membrane anchors in Saccharomyces cerevisiae.

The EMBO journal - 16 Jun 1997

Sipos G, Reggiori F, Vionnet C, Conzelmann A

Abstract excerpt

Glycosylphosphatidylinositol (GPI)-anchored membrane proteins of Saccharomyces cerevisiae exist with two types of lipid moiety--diacylglycerol or ceramide--both of which contain 26:0 fatty acids. To understand at which stage of biosynthesis these long-chain fatty acids become incorporated into diacylglycerol anchors, we compared the phosphatidylinositol moieties isolated from myo-[2-(3)H]inositol-labelled protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyltransferases
Share to Fatty Acids
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Precursors

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Subcellular Fractions

Source

Open in PubMed Open full text

Identifiers

PMID: 9218792
DOI: 10.1093/emboj/16.12.3494
PMCID: PMC1169975

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative lipid remodelling pathways for glycosylphosphatidylinositol membrane anchors in Saccharomyces cerevisiae.PMID 9218792Read ↗

Biosynthesis of glycophosphoinositol anchors in Saccharomyces cerevisiae.Semantic proximity Read ↗

Determination and physiological roles of the glycosylphosphatidylinositol lipid remodelling pathway in yeast.Semantic proximity Read ↗

Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides.Semantic proximity Read ↗

GUP1 of Saccharomyces cerevisiae encodes an O-acyltransferase involved in remodeling of the GPI anchor.Semantic proximity Read ↗

Generating anchors only to lose them: The unusual story of glycosylphosphatidylinositol anchor biosynthesis and remodeling in yeast and fungi.Semantic proximity Read ↗

Fatty acid remodeling of GPI-anchored proteins is required for their raft association.Semantic proximity Read ↗

Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast.Semantic proximity Read ↗

C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p.Semantic proximity Read ↗

CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae.Semantic proximity Read ↗

Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis.Semantic proximity Read ↗

PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.Semantic proximity Read ↗

Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.