Article

Functional mapping of N-terminal residues in the yeast proteome uncovers novel determinants for mitochondrial protein import

2022-08-19

Abstract excerpt

<h4>ABSTRACT</h4> N-terminal ends of polypeptides are critical for the selective co-translational recruitment of N-terminal modification enzymes. However, it is unknown whether specific N-terminal signatures differentially regulate protein fate according to their cellular functions. In this work, we developed an in-silico approach to detect functional preferences in cellular N-terminomes, and identified in S. ce...

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Literature Corpus work: 7cf2185c-7232-5291-84be-f0087e2cdc24
DOI: 10.1101/2022.08.19.504527

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