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Article

Membrane ruffling and macropinocytosis in A431 cells require cholesterol.

Journal of cell science - 15 Jul 2002

Grimmer Stine, van Deurs Bo, Sandvig Kirsten

Abstract excerpt

Cholesterol is important for the formation of caveolea and deeply invaginated clathrin-coated pits. We have now investigated whether formation of macropinosomes is dependent on the presence of cholesterol in the plasma membrane. Macropinocytosis in A431 cells was induced by the phorbol ester 12-O...

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Identifiers

PMID: 12082155
DOI: 10.1242/jcs.115.14.2953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12082155-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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