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Article

Arf6, JIP3, and dynein shape and mediate macropinocytosis.

Molecular biology of the cell - 1 Jun 2019

Williamson Chad D, Donaldson Julie G

Abstract excerpt

Macropinocytosis is an actin-driven form of clathrin-independent endocytosis that generates an enlarged structure, the macropinosome. Although many studies focus on signaling molecules and phosphoinositides involved in initiating macropinocytosis, the commitment to forming a macropinosome and the handling of that membrane have not been studied in detail. Here we show in HT1080 cells, a human fibrosarcoma cell...

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Identifiers

PMID: 30969891
DOI: 10.1091/mbc.E19-01-0022
PMCID: PMC6724687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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