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Article

Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism.

Traffic (Copenhagen, Denmark) - 1 Feb 2005

Grimmer Stine, Ying Ming, Wälchli Sébastien, van Deurs Bo, Sandvig Kirsten

Abstract excerpt

It was recently demonstrated that an increase in the cellular cholesterol level leads to vesiculation of the Golgi apparatus. This vesiculation affects the entire Golgi apparatus and is a reversible process. We have now started to elucidate the mechanism behind this cholesterol-induced vesiculation of the Golgi apparatus. Transient transfection of cells with dominant negative mutant constructs of dynamin 1 and 2...

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Identifiers

PMID: 15634214
DOI: 10.1111/j.1600-0854.2005.00258.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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