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Article

Matrix assembly, cell polarization, and cell survival: analysis of peri-implantation development with cultured embryonic stem cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Li Shaohua, Yurchenco Peter D

Abstract excerpt

A variety of mutations, including those affecting laminin expression and basement membrane, cause early embryonic lethality in the peri-implantation period. However, low cell numbers and inaccessibility of these small embryos make it difficult to study the molecular mechanisms that underlie these defects. Embryoid bodies cultured as suspended spherical cell aggregates derived from normal and defective embryonic...

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Identifiers

PMID: 16845988
DOI: 10.1385/1-59745-037-5:113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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