Article
Linkage disequilibrium analysis in the genetically isolated Norfolk Island population.
Heredity - 1 Apr 2008
Bellis C, Cox H C, Ovcaric M, Begley K N, Lea R A, Quinlan S, Burgner D, Heath S C, Blangero J, Griffiths L R
Abstract excerpt
Norfolk Island is a human genetic isolate, possessing unique population characteristics that could be utilized for complex disease gene localization. Our intention was to evaluate the extent and strength of linkage disequilibrium (LD) in the Norfolk isolate by investigating markers within Xq13.3 and the NOS2A gene encoding the inducible nitric oxide synthase. A total of six microsatellite markers spanning...
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