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Article

Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.

Neuroscience research - 1 May 2002

Saegusa Hironao, Matsuda Yoshihiro, Tanabe Tsutomu

Abstract excerpt

Recently several mutant mouse lines lacking neuronal voltage-dependent Ca(2+) channels (VDCCs) have been established by the use of gene targeting in embryonic stem cells. Pain-related behaviors in Ca(v)2.2 (alpha(1B)) and Ca(v)2.3 (alpha(1E)) knockout mice were studied to gain further insight into the mechanism of pain transmission, where VDCCs are thought to play important roles. We review here the data from...

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Identifiers

PMID: 12074836
DOI: 10.1016/s0168-0102(02)00017-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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