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Article

Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat.

Biochemical and biophysical research communications - 28 Jun 2002

Dobbins David E, Sood Raman, Hashiramoto Akira, Hansen Carl T, Wilder Ronald L, Remmers Elaine F

Abstract excerpt

Osteopetrosis results from a heterogeneous group of congenital bone diseases that display inadequate osteoclastic bone resorption. We recently mapped tl (toothless), a mutation that causes osteopetrosis in rats, to a genetic region predicted to include the rat Csf1 gene. In this study, we sequenced the coding sequence of the rat Csf1 gene to determine if a mutation in Csf1 could be responsible for the tl...

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Identifiers

PMID: 12074592
DOI: 10.1016/S0006-291X(02)00598-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat.PMID 12074592Read ↗

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