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Article

Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain.

Blood - 15 Jan 2006

Nandi Sayan, Akhter Mohammed P, Seifert Mark F, Dai Xu-Ming, Stanley E Richard

Abstract excerpt

The primary macrophage growth factor, colony-stimulating factor-1 (CSF-1), is homodimeric and exists in 3 biologically active isoforms: a membrane-spanning, cell-surface glycoprotein (csCSF-1) and secreted glycoprotein (sgCSF-1) and proteoglycan (spCSF-1) isoforms. To investigate the in vivo role of the chondroitin sulfate glycosaminoglycan (GAG) chain of spCSF-1, we created mice that exclusively express, in a...

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Identifiers

PMID: 16210339
DOI: 10.1182/blood-2005-05-1822
PMCID: PMC1895624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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