Article
Investigation of HLA-DPA1 genotypes as predictors of inflammatory bowel disease in the German, South African, and South Korean populations.
International journal of colorectal disease - 1 Jul 2002
Lantermann Annette, Hampe Jochen, Kim Won H, Winter Trevor A, Kidd Mark, Nagy Marion, Fölsch Ulrich R, Schreiber Stefan
Abstract excerpt
BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) is a polygenic disorder, as demonstrated by epidemiological evidence, genetic linkage, and the identification of the first susceptibility gene, NOD2. Genetic linkage analysis has identified and replicated several genomic regions as locations for susceptibility genes, including chromosome 6p (termed IBD3). The HLA-DP genes play an important role in antigen...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
