Article
Autologous mixed lymphocyte responses in experimentally-induced arthritis of the Lewis rat.
Autoimmunity - 1 Mar 2002
Catchpole Brian, Hamblin Anne S, Staines Norman A
Abstract excerpt
Lewis rats develop immune-mediated arthritis following injection with a variety of agents including bovine type II collagen (bCII), mycobacteria, muramyl dipeptide and CP20961. Since susceptibility to experimentally-induced arthritis has been linked to the genes encoding the major histocompatibility complex, it is hypothesized that antigen presentation to autoreactive T-cells is a critical event in the...
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