Article
Arabidopsis map-based cloning in the post-genome era.
Plant physiology - 1 Jun 2002
Jander Georg, Norris Susan R, Rounsley Steven D, Bush David F, Levin Irena M, Last Robert L
Abstract excerpt
Map-based cloning is an iterative approach that identifies the underlying genetic cause of a mutant phenotype. The major strength of this approach is the ability to tap into a nearly unlimited resource of natural and induced genetic variation without prior assumptions or knowledge of specific genes. One begins with an interesting mutant and allows plant biology to reveal what gene or genes are involved. Three...
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